Jobs -> The Scripps Research Institute - Sundrud Lab

Business Name The Scripps Research Institute - Sundrud Lab
Your Business Type Academia
Logo / Photo
Contact Details
Contact Name Amber Delmas Eliason
Position (Director / Supervisor / etc) Lab Manager
Website URL
Email adelmas(at)
Office Address
Street Address 130 Scripps Way
City / Town Jupiter
Province/ State FL
ZIP / Post Code 33458
Country USA
About This appointment will focus on the local regulation of mucosal T cell function by bile acids in the small intestine. The Sundrud lab has recently demonstrated that circulating T cells sense and respond to the presence of locally-reabsorbed bile acids in the ileum to maintain homeostasis and suppress the development of small bowel inflammatory disease (PMID: 29262351); the lab has new R01-level funding to explore the T cell-intrinsic functions of ligand-operated nuclear receptors in T cell-bile acid cross-talk in the intestine.

The successful candidate will contribute to all aspects of the project, including both in vitro and in vivo T cell analyses, molecular cloning, retroviral T cell transduction experiments, as well as execution and analysis of high-content flow cytometry, RNA-seq, DNA-seq and ATAC-seq experiments. Experience with cloning, T cell culture, animal models of autoimmune and chronic inflammation, and next-generation sequencing is required. Expertise in CRISPR/Cas9 gene editing, shRNAmir-mediated gene knockdown and bile acid physiology are preferred but not required. The successful candidate must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

The successful candidate will work in a fast-paced and dynamic group environment and will be supported by a full-time Senior Research Assistant. Here the Florida campus of The Scripps Research Institute offers strong, well resourced, collabrative science and a high quality-of-life in the beachfront town of Jupiter, Florida.

Listing jobs posted by The Scripps Research Institute - Sundrud Lab

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Date Description Location
Apr-23-2019 Scripps FL - Sundrud Lab Post-Doc Position
Posted By: The Scripps Research Institiute Category: Full-time
<p style="box-sizing: inherit; margin: 0px 0px 1.6em; font-family: " droid="" new="">This appointment will focus on the local regulation of mucosal T ...
Jupiter, FL
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