Jobs -> Ben-Gurion University of the Negev

Business Name Ben-Gurion University of the Negev
Your Business Type Academia
Logo / Photo
Contact Details
Contact Name Prof. Michael Meijler
Position (Director / Supervisor / etc) Principal Investigator
Website URL
Email meijler(at)
Office Address
Street Address Ben Gurion Blvd 1
City / Town Be'er Sheva
Country Israel
About Research Interests: Chemical Biology, Bioorganic Synthesis, Quorum Sensing, Bacterial-Eukaryotic Communication, Molecular Basis of Pathogenesis

Cell-Cell chemical communication
The Meijler group studies the chemical and biological roles of bacterial intra- and interspecies signaling molecules. Cell-to-cell communication is used by single-cell organisms to coordinate their behavior and function in such a way that they can adapt to changing environments and possibly compete with multicellular organisms. Chemical communication amongst bacteria has been termed ‚quorum sensing‚ (QS). Examples of QS-controlled behaviors are biofilm formation, virulence factor expression, antibiotic production and bioluminescence. These processes are beneficial to a bacterial population only when they are carried out in a coordinated fashion. Quorum sensing systems exist in both Gram-positive and -negative bacteria and a variety of oligopeptides and N-acyl-homoserine lactones have been identified as QS molecules. Many QS molecules have not been characterized fully, and we continuously aim to clarify the role of various QS molecules in bacterial signaling (in species such as Pseudomonas aeruginosa, Vibrio cholerae, Salmonella typhimurium, Helicobacter pylori) through synthesis and evaluation of QS molecules and potential antagonists and we develop methodologies to study a wide variety of newly discovered and undiscovered QS molecules.

Bacterial-Eukaryotic Interkingdom Signaling
Recent reports have shown that several QS molecules can also have a direct effect on eukaryotes. The prime area of interactions between QS signals and higher organisms is presumed to be the innate immune system, whose main function is to detect the presence of invading micro-organisms and viruses. It is very likely that eukaryotes have developed mechanisms to sense the QS molecules that bacteria use to assess their cell density, since that would enable a rapid response that is correlated with the size of the bacterial population. We will investigate the interactions between QS molecules and potential receptors in eukaryotes that are expected to trigger an immune response. These investigations will further our understanding of the complex interactions that exist between bacteria and humans, and of certain mechanisms that the immune system uses to control both benign and pathogenic bacterial populations.

Listing jobs posted by Ben-Gurion University of the Negev

Listing 313 jobs posted within 1600 days!

Date Description Location
Jan-21-2019 Postdoctoral Fellow in Chemical Biology / Chemical Proteomics
Posted By: Ben-Gurion University of the Negev Category: Full-time
 The Meijler group is searching for a talented chemical biologist with experience in the use of small molecule probes to study biological systems. Th...
Be'er Sheva, Israel
Supplementary Results
Feb-20-2019 Scientific Software Developer (Biology or chemistry Information System
Our client a pharmaceutical company is looking for a Scientific Developer (Software development in B
Basel, Switzerland
Feb-20-2019 UX Designer - Ireland - Contract up to 6 months - up to €550 Per day
Our client, a Global FinTech company based in the North of Ireland, is looking for an experienced UX
Feb-20-2019 User Researcher- Permanent
User Researcher: Plan, design and conduct in-house usability testing sessions to support the design
London, United Kingdom
Feb-20-2019 Back-end developer Java - AWS
Back end developer Java AWSIn this role, you have the opportunity toParticipate in innovative Resear
Eindhoven, Netherlands
Feb-20-2019 Data Modeler
Job Description and Requirements: Job Title: Data Modeler Duration: 06 Months (possibility to extend
Durham, North Carolina, United States
Feb-20-2019 Systems Engineer
Note: This is not a C2C opportunity. This a 6 Month Contract with the Right to Hire after 6 months.
Florida, United States
Feb-20-2019 Lead Network Engineer
Lead Network Engineer The Senior IS Network Engineer will be required to demonstrate the following s
Knoxville, Tennessee, United States
Feb-20-2019 Network Engineer III
Network Engineer III Network Operations Group, troubleshooting, market data, mutlicast, routing, wir
Chicago, Illinois, United States
Feb-20-2019 Network Engineer
Network Engineer Looking for a strong Network Engineer - preferably from a low latency environment w
New York, New York, United States
Feb-20-2019 Navigation Systems Engineer
Outline of duties:In this role you will support the delivery of secured navigation which can be depe
Malvern, Worcestershire, United Kingdom
Feb-20-2019 Demand Generation Marketing Manager - IT Industry - home based with GC
Demand Generation Marketing Manager with extensive IT Industry experience required to join our clien
United Arab Emirates
Electronic Design Engineer | Hardware Engineer | Hardware Development | ElectronicsPCB | C | C++ | J
Windsor, Berkshire, United Kingdom
Feb-20-2019 Senior new product development engineer- Mechanical design
A Senior mechanical design engineer is required to work within a project team to develop high precis
Berkshire, United Kingdom
Feb-20-2019 Junior Customer Services Specialist
You are an outstanding Customer Service Specialist? Your profession is your passion? You're a proble
Fribourg, Fribourg, Switzerland
Feb-20-2019 Network Automation Engineer
Network Automation Engineer Responsibilities Juggle numerous project implementation and design init
Chicago, Illinois, United States
Feb-20-2019 Network Automation Engineer III
Network Automation Engineer III Responsibilities Juggle numerous project implementation and design
Chicago, Illinois, United States
Feb-20-2019 Junior Operational Analysis Support
The main role for this junior contractor position is to conduct range of OA- related tasks in suppor
Den Haag, Zuid-Holland, Netherlands
Feb-20-2019 Cash Application Specialist
We are seeking a detail-oriented individual to handle cash application processes. Responsibilities i
Independence, Ohio, United States
Feb-20-2019 Workload Planning Administrator
A Workload Planning Administrator is required at the University of Exeter. The role involves inputti
Exeter, Devon, United Kingdom