Jobs -> Johns Hopkins School of Medicine

Business Name Johns Hopkins School of Medicine
Your Business Type Academia
    
Contact Details
Contact Name Hanseok Ko
Position (Director / Supervisor / etc) Associate Professor
Website URL http://www.hopkins-ice.org/neuro/index.h tml
Email hanseok0807(at)gmail.com
Telephone 410-502-5454
Office Address
City / Town Baltimore,
Province/ State Maryland
ZIP / Post Code 21205
Country USA
About
About The overarching goal of my scientific work has been to define key molecular pathways in the pathogenesis of Parkinson's disease (PD) and to identify novel targets for therapeutic development. Our lab is focused on pathways that are critical for understanding the neurodegenerative process as follows:

1. Mechanisms that initiate and govern the conformational conversion of soluble α-synuclein proteins into insoluble amyloid fibrils.
2. Mechanism that underlies gut to brain transmission of pathological α-synuclein and development of the gut-brain α-synuclein transmission mouse model.
3. The downstream neurotoxic effects of aggregated α-synuclein proteins with emphasis on oxidative stress, mitochondrial dysfunction, and the autophagic / lysosomal degradation system.
4. Defining the role and molecular characteristics of neuroinflammation in PD.
5. How dysfunction of mutated GBA1 leads to PD or how GBA1 becomes dysfunctional in the absence of mutations in sporadic PD.

Listing jobs posted by Johns Hopkins School of Medicine

Listing 449 jobs posted within 1600 days!

Date Description Location
Jun-07-2018 Postdoctoral fellow_Johns Hopkins School of Medicine
Posted By: Johns Hopkins School of Medicine Category: Full-time
Employer: Department of Neurology, Institute for Cell Engineering, Johns Hopkins School of Medicine Website: http://www.hopkins-ice.org/neuro/index.h...
Baltimore, MD
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