Jobs -> Barlow laboratory

Business Name Barlow laboratory
Your Business Type Academia
    
Contact Details
Contact Name Jacqueline Barlow
Position (Director / Supervisor / etc) Principal Investigator
Website URL http://microbiology.ucdavis.edu/barlow/
Email jhbarlow(at)ucdavis.edu
Office Address
City / Town Davis
Province/ State CA
Country USA
About
About The focus of the Barlow laboratory is to elucidate the molecular and genetic factors governing how DNA damage arises in response to replicative stress using the mouse immune system as a model. The primary research aim of the laboratory is to investigate how replication stress induces DNA damage in highly proliferative cell types such as B and T lymphocytes, and to understand the mechanisms maintaining genome integrity during DNA replication. The laboratory uses a combination of genetics, molecular biology, and next-generation sequencing to investigate where and how DNA damage arises, define mechanisms controlling cancer initiation and evolution, and identify novel molecular determinants underlying cancer predisposition. The Barlow laboratory is in the Department of Microbiology and Molecular Genetics.
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