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Research Associate/Sr Research Associate Drug Discovery

Posted by: H3 Biomedicine

Posted date: Jan-30-2012

Location: Cambridge, MA

Research Associate/Sr Research Associate – Drug Discovery
Location: Cambridge, MA
Job Code: 11-10TD
We are seeking a Research Associate/Sr Research Associate for the Drug Discovery Biology Group at H3 Biomedicine. The individual will be energetic, self-motivated with a desire to succeed at the highest level joining a team of scientists aiming to develop unique anti-cancer compounds for targeted patient populations. The individual will interact with other team members to design and execute molecular and cell biology experiments aimed at defining the mechanism of action of compounds in appropriate genomic backgrounds that represent susceptible patient populations. Significant cross-functional collaboration with a talented and dedicated group of scientists including biochemists, cell biologists, bioinformaticians and chemists will ensure a diverse exposure to the drug discovery process. As part of the team the candidate will have significant responsibility to drive success of their own project with opportunities to acquire new skills in an innovative and fast-paced environment. The position offers the opportunity to take part in the rapid translation of pre-clinical work to application of compounds in the clinical setting.
Principal Duties and Responsibilities
Developing, optimizing and performing cell based assays to characterize the mechanism of action of anti-cancer compounds
Characterization of cancer cell models from cell line and primary tumor tissues to be used in drug discovery and development efforts
Maintenance of laboratory records, procedures and summaries of data
Perform laboratory experiments and report data and suggest future work to management and project teams
 Qualifications:
  • BS/MS or equivalent;
  • 2-5+ years of industrial/academic laboratory experience;
  • Proven ability  to work independently and design experiments, trouble shoot, interpret and report data back to teams
  • Experience with cell and molecular biology assays including maintenance of mammalian cell cultures, growth and survival assays, immunoassays, si/shRNA techniques
  • Familiarity with medium and high-throughput cell based assays
  • Highly analytical mind, attention to detail, and organization skills are critical;
  • Collaborative and proactive attitude.
  • Excellent written and oral communication skills
H3 Biomedicine Inc. is a privately-held, uniquely-structured oncology discovery enterprise whose sole mission is to become a prolific source of new drugs that treat more human cancers with greater success. H3 Biomedicine is applying the expertise of leading scientists to the integration of insights from cancer genomics with innovative capabilities in synthetic chemistry and tumor biology to pursue the most promising current opportunity in cancer therapeutics: patient-based, genomics-driven, small molecule drugs
Interested candidates may forward a CV to h3_careers(at)h3biomedicine.com
www.h3biomedicine.com
Job Title Research Associate/Sr Research Associate Drug Discovery
Post Details
Email h3_career(at)H3biomedicine.com
Empolyer's Website www.h3biomedicine.com
Category
Job Discipline Job Discipline -> Cancer/Oncology
Job Classification Job Classification -> Research Associate
Job Type Job Type -> Full-time
Location Cambridge, MA
Key Words Oncology
Start Date 02/29/2012
Deadline Mar-01-2012