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Post DOC

Posted by: IEO

Posted date: Dec-27-2018

Location: Milano

Role of RNA-binding proteins in Myc-induced lymphomagenesis. 

A post-doctoral position starting April 1st, 2019,is available to work under the supervision of Dr. Arianna Sabò in the group of Dr. Bruno Amati, at the European Institute of Oncology (IEO, Milan, Italy). IEO is a leading center for Biomedical Research in Europe characterized by an international research environment, interdisciplinary training, access to state-of-the-art technology platforms, and on-campus lectures and workshops for career development. Web:
https://www.ieo.it/it/Corso-EPiServer/Departmen t-of-Experimental-Oncology1/


A major research focus in our group is to unravel the molecular mechanisms underlying the oncogenic activity of the MYC transcription factor, and to exploit them for therapeutic development. Among others, genes encoding RNA-binding proteins (RBPs) have emerged as possible MYC effectors: the successful candidate will address the function and therapeutic potential of select RBPs in MYC-driven lymphomagenesis. Relevant publications of the group include Sabò et al. Nature511, 488-492 (2014), Koh et al. Nature523, 96-100(2015); Kress et al. Nat. Rev. Cancer 15, 593-607 (2015);Koh et al. BioEssays 38, 266-75 (2016); D' Andrea et al. Oncotarget7, 72415-30 (2016); Ravà et al. Sci Transl. Med. 10, eaan8723(2018). The project will combine advanced animal tumor models with state-of-the-art genomic, epigenomic and computational approaches, and will benefit from a highly integrated, multidisciplinary and supportive research environment. 


We seek to recruit an ambitious, self-motivated and team-oriented scientist with a recent PhD in life sciences, a strong background in molecular and/or cancer biology, and a strong interest in working with in vivotumor models. Experience with genomic approaches and/or mouse biology will be an asset. Excellent spoken and written communication skills in English are required.

Interested candidates should send a motivation letter and CV with the names and contacts of three referees to arianna.sabo(at)ieo.it.
Job Title Post DOC
Post Details
Email arianna.sabo(at)ieo.it
Employer's Website www.ieo.it
Job Discipline Job Discipline -> Cancer/Oncology
Job Classification Job Classification -> Postdoctoral Researcher
Job Type Job Type -> Full-time
Location Milano
Key Words postdoc, Myc, cancer, genomic, mouse
Start Date 1 april 2019