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Postdoctoral Research Fellow - Immuno-Oncology

Posted by: Albert Einstein College of Medicine

Posted date: Nov-19-2018

Location: Bronx, NY

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mso-bidi-font-family:"Helvetica Neue";color:#262626">POSITION SUMMARY:</span></b><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:"Helvetica Neue";
color:#262626"> The successful candidate will perform research studies in the area of tumor immunology and autoimmunity. The laboratory is investigating radiation and ultrasound-based <i style="mso-bidi-font-style:normal">in situ</i> vaccines. The goal is to investigate the mechanisms of energy-based immunomodulation, induction of DAMP signals and characterization of innate and adaptive tumor immunity in murine models of solid tumors and in clinical trials in patients; including validation of therapeutic cancer targets using cell-based assays and preclinical cancer models in combination with energy-based treatments for cancer therapies.</span></p>
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<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">This exciting opportunity is within the lab of Dr. Chandan Guha. With 14 patents and extensive research outcomes from various “energy” based therapies beginning in the early 90’s, Dr. Guha serves on numerous boards and is well known as a pioneer in therapeutic ultrasound, radiation and other energy-based therapies. He has generated over $10m in NIH research grants accelerating the need for this position and advancing research. </span></p>
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<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">Future opportunity may exist for successful candidates to participate in a commercial enterprise or incubator as a result of this appointment. </span></p>
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mso-bidi-font-family:"Helvetica Neue";color:#262626">RESPONSIBILITIES:</span></b><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:"Helvetica Neue";
color:#262626"> The successful candidate will execute studies aimed at drug discovery and development in the fields of immune-oncology and radiation-oncology. The candidate is expected to execute </span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:Arial;color:#1A1A1A">in <span style="mso-bidi-font-weight:
bold">vitro/cell based assays</span>, <span style="mso-bidi-font-weight:bold">biomarker analysis</span> of preclinical samples, <span style="mso-bidi-font-weight:bold">flow cytometry, ELISA (ELIspot), PCR, functional in vitro assays and to isolate and culture primary immune cells from murine tissue. The candidate should demonstrate </span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:black;mso-themecolor:text1">strong attention to details, ability to work with a dynamic team, flexibility, reliability and good communicative skills.</span></p>
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mso-pagination:none;mso-layout-grid-align:none;text-autospace:none"><b><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:"Helvetica Neue";
color:#262626">EXPERIENCE AND REQUIRED SKILLS</span></b><span style="font-family:
"Calibri",sans-serif;mso-bidi-font-family:"Helvetica Neue";color:#262626;
mso-bidi-font-weight:bold">:</span></p>
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inter-ideograph;text-indent:-13.5pt;mso-pagination:none;mso-list:l0 level1 lfo1;
tab-stops:11.0pt;mso-layout-grid-align:none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-fareast-font-family:Calibri;
color:#262626"><span style="mso-list:Ignore">•<span style="font:7.0pt "Times New Roman"">    </span></span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626">Advanced degree, M.D./Ph.D. </span><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:"Helvetica Neue";
color:black;mso-themecolor:text1">in immunology, biochemsitry, biomedical sciences (or related study) with an interest and experience (1-2 years) in the field of immunology </span>or oncology</p>
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none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626"> </span></p>
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mso-bidi-font-family:"Helvetica Neue";color:#262626">TECHNICAL SKILLS REQUIRED:</span></b></p>
<p class="MsoNormal" style="margin-left:13.5pt;text-align:justify;text-justify:
inter-ideograph;text-indent:-13.5pt;mso-pagination:none;mso-list:l1 level1 lfo2;
tab-stops:11.0pt 13.5pt;mso-layout-grid-align:none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-fareast-font-family:Calibri;
color:#262626"><span style="mso-list:Ignore">•<span style="font:7.0pt "Times New Roman"">    </span></span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626">Knowledge of the basics of cellular and molecular immunology, as it applies to cancer</span></p>
<p class="MsoNormal" style="margin-left:13.5pt;text-align:justify;text-justify:
inter-ideograph;text-indent:-13.5pt;mso-pagination:none;mso-list:l1 level1 lfo2;
tab-stops:11.0pt 13.5pt;mso-layout-grid-align:none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-fareast-font-family:Calibri;
color:#262626"><span style="mso-list:Ignore">•<span style="font:7.0pt "Times New Roman"">    </span></span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626">Isolation and characterization of primary immune cells from murine tissues (spleen, draining lymphnodes, tumors)</span></p>
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inter-ideograph;text-indent:-13.5pt;mso-pagination:none;mso-list:l1 level1 lfo2;
tab-stops:11.0pt 13.5pt;mso-layout-grid-align:none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-fareast-font-family:Calibri;
color:#262626"><span style="mso-list:Ignore">•<span style="font:7.0pt "Times New Roman"">    </span></span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626">Expertise in sterile cell culture techniques, and in vitro/ex vivo immune cell-based assays</span></p>
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"Helvetica Neue";color:#262626"> </span></p>
<p class="MsoNormal" style="margin-left:.5in;text-align:justify;text-justify:
inter-ideograph;text-indent:-.5in;mso-pagination:none;mso-list:l1 level1 lfo2;
tab-stops:11.0pt .5in;mso-layout-grid-align:none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-fareast-font-family:Calibri;
color:#262626"><span style="mso-list:Ignore">•<span style="font:7.0pt "Times New Roman"">    </span></span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626">Expertise in FACS methods</span></p>
<p class="MsoNormal" style="margin-left:13.5pt;text-align:justify;text-justify:
inter-ideograph;text-indent:-13.5pt;mso-pagination:none;mso-list:l1 level1 lfo2;
tab-stops:11.0pt 13.5pt;mso-layout-grid-align:none;text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-fareast-font-family:Calibri;
color:#262626"><span style="mso-list:Ignore">•<span style="font:7.0pt "Times New Roman"">    </span></span></span><span style="font-family:"Calibri",sans-serif;
mso-bidi-font-family:"Helvetica Neue";color:#262626">Ability to perform in vivo experiments of tumor models in both immunocompetent and immunocompromised mice</span></p>
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mso-pagination:none;tab-stops:11.0pt 13.5pt;mso-layout-grid-align:none;
text-autospace:none"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Helvetica Neue";color:#262626"> </span></p>
<p class="Body"><b><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">Submitting Application:</span></b><span style="font-family:
"Calibri",sans-serif;mso-bidi-font-family:"Arial Unicode MS""> please submit via e-mail a curriculum vitae and role related references:</span></p>
<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS""> </span></p>
<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">Chandan Guha M.D., Ph.D.</span></p>
<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">Department of Radiation Oncology</span></p>
<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">Institute for Oncophysics</span></p>
<p class="Body"><span style="font-family:"Calibri",sans-serif;mso-bidi-font-family:
"Arial Unicode MS"">Albert Einstein College of Medicine, Montefiore Medical Center</span></p>
<span style="font-size:12.0pt;font-family:"Calibri",sans-serif;mso-fareast-font-family:
"MS Mincho";mso-fareast-theme-font:minor-fareast;mso-bidi-font-family:"Times New Roman";
mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA">E-mail: <span class="MsoHyperlink"><a href="mailto:CGuha(at)montefiore.org">CGuha(at)montefiore.org</a></span> </span>
Job Title Postdoctoral Research Fellow - Immuno-Oncology
Post Details
Email CGiha(at)montefiore.org
Employer's Website www.einstein.yu.edu
Category
Job Discipline Job Discipline -> Immunology
Job Classification Job Classification -> Postdoctoral Researcher
Job Type Job Type -> Full-time
Location Bronx, NY
Key Words Immunology,Oncology, Radiation, Breast, Prostate, Cancer
Start Date 01/01/2019
Salary 48432
Deadline Jan-31-2019