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Principal/Senior Scientist - Oligonucleotide chemistry

Posted by: Ractigen Therapeutics

Posted date: Jan-06-2018

Location: Nantong, Jiangsu

Ractigen Therapeutics, founded by the pioneers of a paradigm-shifting technology known as RNAa, is the leading RNAa-based pharmaceutical company committed to bringing to market the next generation of oligonucleotide-based medicines. Ractigen is located in a modern biotech industry park of Nantong City of Jiangsu Province (2 h drive from Shanghai), China. We are seeking a highly motivated and experienced candidate having a strong background in oligonucleotide chemistry, oligonucleotide drug technology and discovery.
Responsibilities:
  • Be responsible for setting up and running an oligonucleotide chemistry facility.
  • Lead a team of scientists to provide oligonucleotide synthesis, chemical modification and purification for internal testing.
  • Develop novel medicinal nucleic acid chemistry, conjugates and formulations.
Requirements:
  • MS or PhD in Organic Chemistry.
  • 2-5 years’ experience in academia or industry with nucleotide chemistry.
  • Previous experience in oligonucleotide drug discovery from hit identification to lead optimization and pre-clinical studies.
  • Experience with nucleotide, and solid-phase oligonucleotide synthesis.
  • Experience preparing peptide conjugates of oligonucleotides.
  • Proficient in the use of methods of instrumental chemical analysis, such as NMR, HPLC, MS, FTIR, is essential.
  • Demonstrated ability to plan and execute independent and collaborative research projects.
  • Co-authorship on one or more publications in peer-reviewed scientific journals.
Benefits:
  • Working in a stimulating environment and with an international team of scientists and entrepreneurs;
  • Excellent physical working environment with recreation facilities;
  • Free/subsidized housing;
  • Very competitive salaries with a generous benefit package including bonus and stock options;
  • Talent incentives provided by local governments and competitive talent programs for qualified individuals;
  • Unique experience of working in China, and particularly in Yangtze River Delta Economic Zone which is poised to become the World’s epic center for drug development.
To apply, please send your CV with a cover letter and the contact information of at least 3 references to hr [at} ractigen.com. For more information, visit: http://www.ractigen.com 
Job Title Principal/Senior Scientist - Oligonucleotide chemistry
Post Details
Email hr(at)ractigen.com
Employer's Website www.ractigen.com
Category
Job Discipline Job Discipline -> Drug Development
Job Classification Job Classification -> Senior Scientist
Job Type Job Type -> Full-time
Location Nantong, Jiangsu
Key Words drug development, oligonucleotide, saRNA
Start Date 2018-2-1
Salary 250,000-350,000RMB
Deadline Mar-01-2018