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PhD Fellowship in Molecular Neural Development and Sequencing Technologies

Posted by: University of Copenhagen

Posted date: Jun-09-2017

Location: Copenhagen, Denmark

PhD Fellowship in Molecular Neural Development and Sequencing Technologies
(University of Copenhagen)

Project description:
This project will use molecular tools including iTRAQ proteomics and single cell RNA-sequencing to characterize the progenitor stellate cell populations in the embryonic pig entorhinal cortex. In particular, characterisation of the progenitor cell populations that give rise to the stellate cells will be performed using bioinformatics. Further studies will be performed to derive stellate cells from induced pluripotent stem cells (iPSCs) using cytokines and growth factors identified from the global profiling and bioinformatics analyses. Comparative molecular studies (i.e. RNA-sequencing) will then be performed to assess whether stellate cells derived from Alzheimer disease patient iPSCs have an altered phenotype compared to iPSCs derived from healthy persons.

Required qualifications:
βΆ Masters in Cell Biology, Neuroscience, Neural development, Bioinformatics or related
field
βΆ Knowledge in pluripotent stem cell and/or developmental biology
βΆ Knowledge in neural development
βΆ Knowledge in cellular RNA and protein sequencing technologies
βΆ Experience in the field of neural development is desirable
βΆ Experience with proteomic sequencing and/or transcriptome sequencing is desirable
βΆ Experience with bioinformatics processing of large data sets is desirable
βΆ Experience with culture and differentiation of pluripotent stem cells is desirable
βΆ Experience with molecular methods such as immunohistochemistry, qPCR, westerns and cDNA
library preparation is desirable
βΆ High motivation and basic scientific skills are essential
βΆ Excellent communication skills both oral and written, including fluent use of the English
language
βΆ Excellent collaborating and teamwork skills are essential
βΆ Publication/s in relevant fields of the project is desirable

For more information go to: http://employment.ku.dk
Only online applications are accepted.
Job Title PhD Fellowship in Molecular Neural Development and Sequencing Technologies
Post Details
Email vh(at)sund.ku.dk
Employer's Website ivh.ku.dk
Category
Job Discipline Job Discipline -> Neuroscience
Job Classification Job Classification -> Education & Training
Job Type Job Type -> Full-time
Location Copenhagen, Denmark
Key Words PhD fellowship, neuroscience, sequencing technologies, bioinformatics
Start Date 01.09.2017
Deadline Jul-16-2017