Posted by: Alaka'ina Foundation Family of Companies
Posted date: May-13-2017
Ke’aki Technologies, LLC, is a Native Hawaiian Organization (NHO) owned business. A premier government services company, Ke’aki Technologies, LLC offers a full spectrum of solutions that improve the performance and operational effectiveness of our government and Department of Defense customers. Our mission synchronized solutions are designed to deliver exactly what our customers need, when they need it. From base and range operations to biomedical defense support to telecommunications and IT services, we deliver the exact talent, tools and technologies needed to meet mission requirements.
Ke’aki Technologies is looking for a Toxin Vaccine Research Technical Support employee on our United States Army Medical Research Institute of Infectious Diseases (USAMRIID) contract at Fort Detrick, Maryland.
This employee will conduct basic and applied research on current and emerging threats at BSL2 and BSL3 levels, in support of the biodefense and infectious disease program. The individual will provide expertise in a range of immunological assessments supporting prophylactic and therapeutic product development against botulinum toxin.
Assessment of recombinant protein vaccine antigens in small animal biological assays. This will include vaccine formulation, inoculation of test subjects, administration of challenge toxins, and assessment and quantification of vaccine potency and efficacy. This includes approximately 15-20 animal experiments per year.
Assessment and characterization of immunotherapeutic molecules in both in vitro and in vivo models. This may include determination of antibody titers by ELISA, toxin neutralization assays, passive transfer studies, and assessment of individual immunoglobin preparations.
Produce and characterize challenge toxins from strains expressing toxin variants not commercially available for use in vaccine challenge studies. This may include culturing select agent strains of pathogens, partially clarifying toxin extracts, determining toxin potencies and characterizing toxins by SDS-PAGE, Western blot, and UV spectroscopy.
Characterize new Clostridium botulinum strains as to morphological, biophysical, and genetic characterizations. They will produce cell, spore, crude toxin supernatant, and extracted DNA stocks from C. botulinum cultures. Organize and maintain stocks for efficient inventory, archiving, and retrieval. Collect and organize data on C. botulinum strains.
Prepare animal protocols, standard operating procedures, and other documentation necessary to conduct assigned experiments. The contractor will be responsible for assessing and maintaining laboratory supplies in assigned laboratories. Will assess and ensure that supplies are ordered or will be ordered using the current GFEBS ordering system. Responsible for maintaining assigned laboratory space in compliance with all applicable regulations.
Assist in the preparation of statements of work, annual reports and manuscripts related to their research and assigned tasks. Should present relevant research data atone scientific meeting per year.
Will provide laboratory support with laboratory experiments in BSL-2/3 CDC registered laboratories and thus must hold and maintain BPRP status.
BS with 7 years' experience or MS with 2 years' experience
Eligibility in the Biological Personnel Reliability Program (BPRP) requires a favorable Single Scope Background Investigation (SSBI).
Enrollment in the Biological Personnel Reliability Program (BPRP) for handling select agents - he or she must maintain enrollment. Applicants must meet eligibility requirements as regulated by Army Regulation 50-1 (AR 50-1)- http://www.fas.org/irp/doddir/army/ar50-1.pdf
Ke`aki Technologies LLC is a fast growing government service provider. Employees enjoy competitive salaries; a 401K plan with company match; medical, dental, disability, and life insurance coverage; tuition reimbursement; paid vacation and sick time; and 10 paid holidays. Ke`aki Technologies is proud to be an equal opportunity employer.
For additional information on Ke`aki Technologies, LLC, please visit www.keakitech.com.
We are an Equal Opportunity/Affirmative Action Employer of individuals with disabilities and veterans. We are proud to state that we do not discriminate in employment decisions on the basis of race, color, religion, sex, national origin or disability status. If you are a person with a disability and you need an accommodation during the application process, please click hereto request accommodation. We E-Verify all employees.