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Post-Doc in Recombinant Monoclonal Antibodies

Posted by: Ana Maria Moro

Posted date: Mar-29-2017

Location: Sao Paulo, SP

 Post-Doc Opportunity


A post-doc opportunity is offered by the Biopharmaceuticals in Animal Cells Lab of Instituto Butantan to work in the development of a humanized  anti-CD3 monoclonal antibody. In the past the murine version of the anti-CD3 was produced by the group and tested in the clinic for graft rejection control. Being an immunomodulator with therapeutic potential for tolerance induction, it is mandatory the obtainment of its humanized version. To cope with that, the post-doc candidate should be able to construct vectors for antibody expression with productivity and stability and design the full IgG genes. An alternative humanization process may be necessary.  

Requirements

PhD in Sciences, Genetics, Immunology or Molecular Biology, acquired after 2012.
Capacity to work independently and in a team-oriented environment.
Solid previous experience in molecular biology techniques. 
Knowledge in antibody genes and flow cytometry is appreciated. 
Fluency in English language is required.

Documentation

Candidates should send, until April 28 2017, a research/motivation statement, their CV and two recommendation letters

Location: Instituto Butantan, Av. Vital Brasil 1500, São Paulo, SP

Attention: Dr. Ana Maria Moro

ana.moro(at)butantan.gov.br

Job Title Post-Doc in Recombinant Monoclonal Antibodies
Post Details
Email ana.moro(at)butantan.gov.br
Employer's Website www.fapesp.br
Category
Job Discipline Job Discipline -> Molecular Biology
Job Classification Job Classification -> Postdoctoral Researcher
Job Type Job Type -> Full-time
Location Sao Paulo, SP
Key Words anti-CD3, vector, stable expression, tolerance, autoimmune, IgG, humanization, CDR transplantation
Start Date June 2017
Salary R$ 6.819,30
Deadline Apr-28-2017