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Postdoctoral Fellows

Posted by: University of Macau

Posted date: Jan-11-2015

Location: Macau, China

Summary:Applications are invited for two postdoctoral positions and a research specialist in the area of Human Embryonic Stem Cells (hESCs) and induced Pluripotent Stem Cells (iPSCs) in Dr. Guokai Chen’s group at the University of Macau (http://fhs.umac.mo/staff/academic-staff/chen-guokai/). The lab is interested in the development of new stem cell technologies for translational applications1,2,3,4. The lab currently focuses on stem cell differentiation to specific cell types under chemically defined conditions. It also works on the nutritional regulation on stem cell metabolism. We are seeking highly motivated candidates to join us to explore exciting applications of human pluripotent stem cells.
Responsibilities: The Postdoctoral Fellows will be responsible for developing differentiation procedures to produce specific cell types that could be used in disease discovery and potentially cell therapies. The Postdoctoral Fellows will identify novel factors or procedures that would allow large scale cell differentiation under chemically defined conditions. The Research Specialist will provide technical assistance and stem cell training in the iPSC Core Facility. At the same time, independent research projects will be assigned to develop technologies with urgent needs.
The complexity of stem cell regulations will require a creative mind and a candidate capable of deploying imaginative strategies and who is dedicated to solving complex and challenging problems facing stem cell applications in translational research.
Requirements: Candidates must have a PhD in biology, medicine, bioinformatics, chemistry, or a related field.
Preferences:Preferred requirements for this position include experience in stem cell biology, embryogenesis, metabolic regulation and chemistry. Experience in bioinformatics is a big plus and preferred.
Terms:The positions are available immediately and can be renewed annually.
How to apply: Email applications including curriculum vitae, summary statement of personal objectives, and the names and email addresses of 2-3 references to Guokai Chen (hms.harvard.edu">guokaichen(at)yahoo.com).
Research Environment
The University of Macau (www.umac.mo) is the leading university in Macau, China, and it recently moved to a new 300-Acre campus on Hengqin Island. In 2012, the University established the Faculty of Health Sciences (FHS) that is striving to become a top research Institute in Biomedical Sciences. The FHS consists of top-level laboratories and 10 core facilities, providing an exceptional environment for basic and translational research programs. This new faculty is well-funded by direct funding support from the University and extramural funding opportunity from Macau Foundation.
Financial Support and Living Environment
The salary for this position will be between US$30,000 and US$33,000 depending on the experiences. Also, the living cost in Macau is relatively low. Successful candidates are eligible for residence in the University Housing complex. Macau is a beautiful and historical city just minutes away from mainland China and one-hour ferry away from Hong Kong, and has been thriving with diverse cultures.
1.   Beers J, Gulbranson DR, George N, Siniscalchi LI, Jones J, Thomson JA and Chen G. Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nature Protocols 7, 2029-2040 (2012). 
2.   Chen G, Gulbranson DR, Yu P, Hou Z, Thomson JA. Thermal stability of fibroblast growth factor protein is a determinant factor in regulating self-renewal, differentiation, and reprogramming in human pluripotent stem cells. Stem Cells. 2012 Apr; 30(4): 623-30.
3.   Chen G, Gulbranson DR, Hou Z, Bolin JM, Ruotti V, Probasco MD, Smuga-Otto K, Howden SE, Diol NR, Propson NE, Wagner R, Lee GO, Antosiewicz-Bourget J, Teng JMC and Thomson JA. Chemically defined conditions for human iPS cell derivation and culture. Nature Methods. 2011 April 10; 8(4): 424-429. 
4.   Chen G, Hou Z, Gulbranson DR and Thomson JA. Actin-Myosin Contractility Is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells. Cell Stem Cell. 2010 Aug 6; 7(2):240-8.
Job Title Postdoctoral Fellows
Post Details
Email guokaiche(at)yahoo.com
Employer's Website http://
Job Discipline Job Discipline -> Stem Cell
Job Classification Job Classification -> Postdoctoral Researcher
Job Type Job Type -> Full-time
Location Macau, China
Key Words postdoc, stem cell
Start Date 01/14/2015
Deadline Feb-28-2015